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PROW: CD37
[PROW BAR]
PROW and IWHLDA present the GUIDE on:
CD37
Author: Gerhard Moldenhauer
Reviewer: Vaclav Horejsi
[GUIDE BAR]

ALTERNATE NAMES FOR CD37  

MAJOR LINKS FOR CD37  


FUNCTION
BIOCHEMICAL ACTIVITY OF CD37   - No information

CELLULAR FUNCTION OF CD37  

DISEASE RELEVANCE OF CD37 AND FUNCTION OF CD37 IN INTACT ANIMAL  


STRUCTURE
MOLECULAR FAMILY FOR CD37  

MOLECULAR STRUCTURE OF CD37  

MOLECULAR MASS OF CD37  

CELL TYPEMW UNREDUCEDMW REDUCEDComment
Lymphoblastoid B cell line 40-52 kDa 40-52 kDa  

POST-TRANSCRIPTIONAL MODIFICATION OF CD37   - No information

POST-TRANSLATIONAL MODIFICATION OF CD37  


MOLECULAR INTERACTIONS
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD37   - No information

SUBSTRATES FOR CD37   - No information

ENZYMES WHICH MODIFY CD37   - No information

LIGANDS FOR CD37 AND MOLECULES ASSOCIATED WITH CD37  

MOLECULECOMMENT
CD53 See Note 1
CD81 See Note 1
CD82 See Note 1
MHC class II See Note 1

EXPRESSION
MAIN CELLULAR EXPRESSION OF CD37  
 
AUTHOR'S ADDITIONAL INSIGHTS ON CD37  
REAGENTS
CD37-SPECIFIC MABS NEWLY ASSIGNED AT SIXTH INTERNATIONAL WORKSHOP   - No information

SELECTION OF OTHER CD37-SPECIFIC REFERENCE MAB  

NAME(Workshop IDs)SOURCE or REFERENCECOMMENT
HD28 (Schwartz-Albiez et al. 1988)  
G28-1 (Ledbetter et al., 1987)  
MB-1 (Link et al. 1986)  
M-B371 (P Rieber, Dresden, Germany)  
IPO-24 (Sidorenko et al. 1992)  

 
SELECTED REFERENCES ON CD37  

REVIEWS

1. Wright MD,Tomlinson MG The ins and outs of the transmembrane 4 superfamily. Immunol Today 1994 15:588 PubMed

PRIMARY CITATIONS

2. Angelisova P,Hilgert I,Horejsi V Association of four antigens of the tetraspans family (CD37, CD53, TAPA- 1, and R2/C33) with MHC class II glycoproteins. Immunogenetics 1994 39:249 PubMed

3. Classon BJ,Williams AF,Willis AC,Seed B,Stamenkovic I The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen. J Exp Med 1990 172:1007 PubMed

4. Ledbetter, J.A., Shu, G., and Clark, E.A. 1987. Leucocyte Typing III, pp. 339-340.

5. Link MP,Bindl J,Meeker TC,Carswell C,Doss CA,Warnke RA,Levy R A unique antigen on mature B cells defined by a monoclonal antibody. J Immunol 1986 137:3013 PubMed

6. Schwartz-Albiez R,Dorken B,Hofmann W,Moldenhauer G The B cell-associated CD37 antigen (gp40-52). Structure and subcellular expression of an extensively glycosylated glycoprotein. J Immunol 1988 140:905 PubMed

7. Sidorenko SP,Vetrova EP,Yurchenko OV,Berdova AG,Shlapatskaya LN,Gluzman DF Monoclonal antibodies of IPO series against B cell differentiation antigens in leukemia and lymphoma immunophenotyping. Neoplasma 1992 39:3 PubMed

8. Virtaneva KI,Angelisova P,Baumruker T,Horejsi V,Nevanlinna H,Schroder J The genes for CD37, CD53, and R2, all members of a novel gene family, are located on different chromosomes. Immunogenetics 1993 37:461 PubMed

WWW RESOURCES


* indicates ammended by reviewer, ** indicates added by reviewer

Portions copyright by Garland Press and by the International Workshops on Human Leukocyte Differentiation Antigens; used with permission

Modified 10/14/99   mpr@mail.nih.gov