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PROW: CD1c
[PROW BAR]
PROW and IWHLDA present the GUIDE on:
CD1c (part of CD1 Family)
Authors: Leonardo Fainboim; M. C. Salamone
Reviewer: Cesar Milstein
[GUIDE BAR]

ALTERNATE NAMES FOR CD1c  

MAJOR LINKS FOR CD1c  


FUNCTION
BIOCHEMICAL ACTIVITY OF CD1 Family   - No information

CELLULAR FUNCTION OF CD1 Family  

DISEASE RELEVANCE OF CD1 Family AND FUNCTION OF CD1 Family IN INTACT ANIMAL   - No information


STRUCTURE
MOLECULAR FAMILY FOR CD1c  

MOLECULAR STRUCTURE OF CD1 Family  

MOLECULAR MASS OF CD1 Family  

CELL TYPEMW UNREDUCEDMW REDUCEDComment
Thymocytes CD1a 49 kDa    
Thymocytes CD1b 45 kDa    
Thymocytes CD1c 43 kDa    

POST-TRANSCRIPTIONAL MODIFICATION OF CD1 Family  

POST-TRANSLATIONAL MODIFICATION OF CD1 Family  


MOLECULAR INTERACTIONS
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD1 Family   - No information

SUBSTRATES FOR CD1 Family   - No information

ENZYMES WHICH MODIFY CD1 Family   - No information

LIGANDS FOR CD1 Family AND MOLECULES ASSOCIATED WITH CD1 Family   - No information


EXPRESSION
MAIN CELLULAR EXPRESSION OF CD1 Family  
 
AUTHOR'S ADDITIONAL INSIGHTS ON CD1 Family  
REAGENTS
CD1 Family-SPECIFIC MABS NEWLY ASSIGNED AT SIXTH INTERNATIONAL WORKSHOP  
NAME(Workshop IDs)SOURCE or REFERENCECOMMENT
WuT6 (CD1a) Wang, Z.  
SN13 (CD1b) Seon, B.K.  
VIT6C (CD1a) Knapp, W. (weak reactivity with CD1b,c,d,e)

SELECTION OF OTHER CD1 Family-SPECIFIC REFERENCE MAB   - No information


 
SELECTED REFERENCES ON CD1 Family  

REVIEWS

1. Blumberg RS; Gerdes D; Chott A; Porcelli SA; Balk SP. Structure and function of the CD1 family of MHC-like cell surface proteins. Immunol. Rev. 1995 147:5 PubMed

2. Calabi, F, Yung Yu ,C, Bilsland,C A.G, and Milstein C. In: Immunogenetics of the mayor histocompatibility complex De. Srivastava, R, Ram, B, and Tyle, P. VCH Publishers, New York, 215-243, (1991)

3. Crispe IN; Mehal WZ. Strange brew: T cells in the liver. Immunol. Today 1996 17:522 PubMed

4. Melian A; Beckman EM; Porcelli SA; Brenner MB. Antigen presentation by CD1 and MHC-encoded class I-like molecules. Curr. Opin. Immunol. 1996 8:82 PubMed

PRIMARY CITATIONS

5. Bendelac A; Lantz O; Quimby ME; Yewdell JW; Bennink JR; Brutkiewicz RR. CD1 recognition by mouse NK1+ T lymphocytes. Science 1995 268:863 PubMed

6. Martin LH; Calabi F; Milstein C. Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens. Proc. Natl. Acad. Sci. U.S.A. 1986 83:9154 PubMed

7. Salamone MC; Fainboim L. Intracellular expression of CD1 molecules on PHA-activated normal T lymphocytes. Immunol. Lett. 1992 33:61 PubMed

8. Salamone MC; Roisman FR; Santiago J; Satz ML; Fainboim L. Analysis of CD1 molecules on haematological malignancies of myeloid and lymphoid origin. I. Cell surface antigen expression. Dis. Markers 1990 8:265 PubMed

9. Woolfson A; Milstein C. Alternative splicing generates secretory isoforms of human CD1. Proc. Natl. Acad. Sci. U.S.A. 1994 91:6683 PubMed

10. Yu CY; Milstein C. A physical map linking the five CD1 human thymocyte differentiation antigen genes. EMBO J. 1989 8:3727 PubMed

WWW RESOURCES


* indicates ammended by reviewer, ** indicates added by reviewer

Portions copyright by Garland Press and by the International Workshops on Human Leukocyte Differentiation Antigens; used with permission

Modified 10/14/99   mpr@mail.nih.gov