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PROW: CD88
[PROW BAR]
PROW and IWHLDA present the GUIDE on:
CD88
Author: Teizo Fujita
Reviewer: Francois Boulay
Link to additional info in FORUM
[GUIDE BAR]

ALTERNATE NAMES FOR CD88  

MAJOR LINKS FOR CD88  


FUNCTION
BIOCHEMICAL ACTIVITY OF CD88  

CELLULAR FUNCTION OF CD88  

DISEASE RELEVANCE OF CD88 AND FUNCTION OF CD88 IN INTACT ANIMAL  


STRUCTURE
MOLECULAR FAMILY FOR CD88  

MOLECULAR STRUCTURE OF CD88  

MOLECULAR MASS OF CD88  

CELL TYPEMW UNREDUCEDMW REDUCEDComment
Neutrophil 43 kDa    
Monocytes 43 kDa    

POST-TRANSCRIPTIONAL MODIFICATION OF CD88   - No information

POST-TRANSLATIONAL MODIFICATION OF CD88  


MOLECULAR INTERACTIONS
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD88   - No information

SUBSTRATES FOR CD88   - No information

ENZYMES WHICH MODIFY CD88   - No information

LIGANDS FOR CD88 AND MOLECULES ASSOCIATED WITH CD88  

MOLECULECOMMENT
C5a/C5a(desArg)  
Anaphylatoxin  

EXPRESSION
MAIN CELLULAR EXPRESSION OF CD88 Link to additional info in FORUM  
 
AUTHOR'S ADDITIONAL INSIGHTS ON CD88   - No information


REAGENTS
CD88-SPECIFIC MABS NEWLY ASSIGNED AT SIXTH INTERNATIONAL WORKSHOP  
NAME(Workshop IDs)SOURCE or REFERENCECOMMENT
4C8    
MC512    

SELECTION OF OTHER CD88-SPECIFIC REFERENCE MAB   - No information


 
SELECTED REFERENCES ON CD88  

REVIEWS

1. Gerard C,Gerard NP C5A anaphylatoxin and its seven transmembrane-segment receptor. Annu Rev Immunol 1994 12:775 PubMed

2. Oppermann. 1995. Leukocyte Typing V. 953-954

PRIMARY CITATIONS

3. Boulay F,Mery L,Tardif M,Brouchon L,Vignais P Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells. Biochemistry 1991 30:2993 PubMed

4. Gerard NP,Gerard C The chemotactic receptor for human C5a anaphylatoxin. Nature 1991 349:614 PubMed

5. Hopken UE,Lu B,Gerard NP,Gerard C The C5a chemoattractant receptor mediates mucosal defence to infection. Nature 1996 383:86 ** PubMed

6. Watanabe H,Kuraya M,Kasukawa R,Yanagisawa H,Yanagisawa M,Fujita T Analysis of C5a receptor by monoclonal antibody. J Immunol Methods 1995 185:19 PubMed

7. Ye RD,Boulay F Structure and function of leukocyte chemoattractant receptors. Adv Pharmacol 1997 39:221 PubMed

WWW RESOURCES


* indicates ammended by reviewer, ** indicates added by reviewer

Portions copyright by Garland Press and by the International Workshops on Human Leukocyte Differentiation Antigens; used with permission

Modified 10/14/99   mpr@mail.nih.gov